Innovative Disposable Bioreactors For Membrane Protein Production Based on the Tide Principle

Disposable rocking bioreactors for recombinant protein production in Escherichia coli: Physical characterization and assessment of therapeutic protein expression

Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution.

Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article presents an overview of the engineering cha...

Two new disposable bioreactors for plant cell culture: The wave and undertow bioreactor and the slug bubble bioreactor.

The present article describes two novel flexible plastic-based disposable bioreactors. The first one, the WU bioreactor, is based on the principle of a wave and undertow mechanism that provides agitation while offering convenient mixing and aeration to the plant cell culture contained within the bioreactor. The second one is a high aspect ratio bubble column bioreactor, where agitation and aera...

Effect of Concentration of Cations on Activated Sludge Properties and Membrane Fouling in Membrane Bioreactors for Wastewater Treatment

This paper presents the results of an investigation on the effects of concentration of cations on activated sludge properties and membrane fouling in submerge membrane bioreactors. The working volume of the experimental setup was two liters. The cellulose acetate membrane was immersed in the bioreactor. The flocculability, settling properties and fouling propensity of activated sludge was measu...

On-line monitoring of the live cell concentration in bioreactors based on a rocking platform

Background Aber Instruments first introduced the concept of using disposable live-biomass probes in 2009 [1]. The probe has been carefully designed to be welded into most single use bioreactors and is suitable for bags with agitators eg the Hyclone SUB and the Sartorius Stedim Biostat Cultibag STR, or those using the rocker type platform eg Sartorius Stedim Biostat Cultibag RM and GE Wave biore...